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Polypeptide Pentadecapeptide Bpc 157 Human Growth Peptides for Bodybuilding

HONGKONG YUANCHENG GONGCHUANG TECHNOLOGY Co., LIMITED
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Polypeptide Pentadecapeptide Bpc 157 Human Growth Peptides for Bodybuilding

Brand Name : ChineseHormone
Model Number : 137525-51-0
Certification : ISO9001,SGS,UKAS
Place of Origin : China
MOQ : Free samples Available
Price : Negotiable
Payment Terms : Western Union, MoneyGram, T/T,Bitcoins
Supply Ability : 10000-30000iu/month
Delivery Time : 3-6 working days
Packaging Details : 10iu/vial, 10vials/kit
Sequence : Gly-Glu-Pro-Pro-Pro-Gly- Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
MF : C62H98N16O22
MW : 1419.53552
Purity : 99%
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Customization Accepted Peptides Pentadecapeptide Bpc 157 Body Building Hormone


BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models. In fact, preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease.


BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect. In addition, it significantly facilitates the healing of bone fracture in rats.


This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect. BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle.

FITC-phalloidin staining was able to demonstrate that BPC 157 induces F-actin formation in fibroblasts. Likewise, Western blot analysis was able to detect the production and activation of paxillin and FAK proteins.


The western blot analysis also showed that BPC 157 increases the extent of phosphorylation of paxillin and FAK proteins without affecting the amounts produced.

BPC 157 (Body Protection Compound-157) is a pentadecapeptide made up of 15 amino acids. The amino acids sequence in BPC 157 is similar to a portion of the human BPC amino acid sequence. Human BPC is found in the gastric juice.


Experiments have shown that BPC 157 enhances the healing of wounds, including tendons wounds such as transected Achilles tendons of rats. The aim of this study was to investigate the probable mechanism that BPC 157 utilizes to accelerate the healing process in an injured tendon.


The study used two group of tendon explants of which one group was cultured in a BPC 157-containing medium while the other group was cultured in a medium lacking BPC 157. These cultures were thereafter examined for tendon fibroblasts outgrowths. Such outgrowths indicated tendon regeneration.


The results revealed that the explants' outgrowth was significantly accelerated in the culture containing BPC 157 as compared to the culture lacking BPC 157. Also, a MTT assay did show that BPC 157 does not directly affect cellular proliferation in a culture of rat-derived Achilles tendon.


However, results also showed that BPC 157 significantly increased the survival of cells under oxidative stress. Furthermore, the Transwell filter migration assay showed that BPC 157 significantly increased in-vitro fibroblast migration in a dose-dependent fashion.


Moreover, BPC 157 accelerated the dispersal of the fibroblasts in culture dishes in a dose-dependent manner.


Function:

BPC 157-treated cells was significantly increased under the H(2)O(2) stress. BPC 157 markedly increased the in vitro migration of tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes.


The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered.


BPC 157 and the Gastro-Intestinal Tract


Because of the way in which BPC 157's inherent mechanics operate in conjunction with an animal test subject's digestive tract, scientific studies have produced several hypothetical ways in which the peptide could provide aid regarding specific functions pertaining to the gastro-intestinal tract.


For instance, it is thought that the peptide's wound-healing and anti-inflammatory properties could provide aid in the treatment to various inflammatory bowel diseases such as Chron's disease and ulcerative colitis.


The anti-inflammatory properties have also allowed the peptide to be linked to conceivable quelling the effects of periodontitis around the teeth.


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MGF2mg
PEG MGF2mg
CJC-1295 with DACv2mg
CJC-1295 without DAC2mg
PT-14110mg
MT-110mg
MT-210mg
GHRP-25mg
GHRP-210mg
GHRP-65mg
GHRP-610mg
Ipamorelin2mg
Hexarelin2mg
Sermorelin2mg
Oxytocin2mg
TB5002mg
Pentadecapeptide BPC 1572mg
Triptorelin2mg
Tesamorelin2mg
Gonadorelin2mg
Gonadorelin10mg
DSIP2mg
Selank5mg


Purely for Scientific Research


Despite the fact that there has been plenty of research on BPC 157 in relation to how it functions and the benefits that can be derived from such functionality, it should be emphasized that the peptide is still just intended for scientific study at this point in time.


Because of this, any findings or observations relating to BPC 157's overall functionality, mechanics, benefits, should exclusively be the product of study performed in a strictly contained environment.


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Growth Hormone Bodybuilding

      

Human Growth Hormone Supplements

      
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